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Seminar: "Quantifying Brownian, ATP-driven, and physiological motion in tissue with optical coherence tomography: applications in breast cancer and airway disease" by Amy Oldenburg

Thursday, April 6, 2017 11:00 AM to 12:00 PM
CREOL Room 103

Amy Oldenburg
University of North Carolina at Chapel Hill


Phase-sensitive imaging technologies such as optical coherence tomography (OCT) are uniquely suited for quantifying nanoscale motions of intracellular components and exogenous particles within biological tissue, even of those smaller than the resolution of the imaging system. On a larger scale, anatomic OCT (aOCT) employed endoscopically can provide physiological (fluid-driven) tissue motion with higher sensitivity than traditional biomedical imaging modalities. In this presentation a number of technologies and applications will be presented where OCT imaging of motion is used to provide novel insight into breast cancer development, airway pathology and lung disease.


Amy Oldenburg is an Associate Professor of Physics & Astronomy at the University of North Carolina at Chapel Hill, where she directs the Coherence Imaging Laboratory. She received her B.S. in Applied Physics at the California Institute of Technology, and PhD in Physics from the University of Illinois at Urbana-Champaign. Dr. Oldenburg received the NSF CAREER award in Biophotonics in 2014. Her research interests include developing novel imaging methods based upon optical coherence tomography, digital holography, and ultrasound to reveal biomechanical and functional cellular properties for fundamental and translational biomedical research. 

For additional information:

Peter J. Delfyett

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