Giving to CREOL CREOL, The College of Optics & Photonics
Dr. Kyu Young Han

Dr. Kyu Young Han

Assistant Professor of Optics & Photonics

Optical Nanoscopy







Kyu Young Han received his BS and PhD in Chemistry from Seoul National University, Korea in 2004 and 2010. During his PhD, he worked at Max Planck Institute for Biophysical Chemistry in Germany where he achieved ultimate resolution of optical microscopy using stimulated emission depletion (STED) and ground state depletion (GSD) microscopy, and developed affordable time-gated STED. Since 2011, he has been working as a postdoc researcher at the University of Illinois, focusing on designing new optical tools for biological applications such as studying DNA-protein interactions, RNA imaging in live-cells and revealing nuclear structure in mammalian cells. His patent on STED microscopy was commercialized by Leica Microsystems.


Awards & Honors

2016 UCF Faculty Travel Award

Recent Publications

Ian Khaw*, Benjamin Croop*, Jialei Tang, A Möhl, U Fuchs & KY Han
"Flat-field illumination for quantitative fluorescence imaging"
bioRxiv 297242, April 2018
B Hua , Y Wang, S Park, KY Han, D Singh, JH Kim, W Cheng and T Ha
"Single-molecule centroid localization algorithm improves the accuracy of fluorescence binding assays"
Biochemistry 57, 1572–1576
G Je, Benjamin Croop, S Basu, Jialei Tang, KY Han* and YS Kim*
"Endogenous alpha-synuclein protein analysis from human brain tissues using single-molecule pull-down assay"
Analytical Chemisty 89, 13044-13048
Jialei Tang, YY Sun, S Pang and KY Han
"Spatially encoded fast single-molecule fluorescence spectroscopy with full field-of-view"
Sci. Rep. 7, 10945
I Masuda, T Igarasgi, R Sakaguchi, R Nitharwl, R Takase, KY Han, BJ Leslie, C Liu, H Gamper, T Ha, S Sanyal, and YM Hou
"A genetically encoded fluorescent tRNA is active in live-cell protein synthesis "
Nucleic Acids Res., 45, 4081-4093
P. Heo, Y. Yang, K.Y. Han, B. Kong, J. Shin, Y. Jung, C. Jeong, J.H. Shin, Y.K. Shin, T. Ha, and D.H. Kweon
"A chemical controller of SNARE-driven membrane fusion that primes vesicles for Ca2+-triggered millisecond exocytosis"
J. Am. Chem. Soc. 138, 4512-4521
J Kwon, J Hwang, J Park, GR Han, KY Han*, SK Kim*
"RESOLFT nanoscopy with photoswitchable organic fluorophores"
Sci. Rep. 5, 17804
J Zhang, J Fei, BJ Leslie, KY Han, TE Kuhlman, T Ha
"Tandem Spinach array for mRNA imaging in living bacterial cells"
Sci. Rep. 5, 17295
KY Han, T Ha
"Dual-color three-dimensional STED microscopy with a single high-repetition-rate laser"
Opt. Lett. 40, 2653-2656


Science & Technology Skip Navigation Links.
Optoelectronics & Integrated Photonics
Quantum Dots & Nanostructures
Imaging, Sensing & Display
Optical Design & Image Analysis
Biological & Medical Imaging
Applications Skip Navigation Links.
Optical Sensing
Lasers in Medicine
Optical Signal Processing
Contact Webmaster © University of Central Florida
4304 Scorpius St., Orlando FL 32816-2700 | 407-823-6800